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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNX
All Species:
26.67
Human Site:
S1259
Identified Species:
48.89
UniProt:
Q96RV3
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96RV3
NP_055797.2
2341
258676
S1259
E
K
L
R
N
S
V
S
E
R
L
Q
S
D
L
Chimpanzee
Pan troglodytes
XP_510039
2300
254005
V1226
E
R
L
Q
S
D
L
V
V
C
I
V
I
G
V
Rhesus Macaque
Macaca mulatta
XP_001084081
2342
258864
S1260
E
K
L
R
N
S
V
S
E
R
L
Q
S
D
L
Dog
Lupus familis
XP_537501
2332
257280
S1250
E
K
L
R
N
S
V
S
E
R
L
Q
S
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QYC1
2344
258128
S1262
E
K
L
S
N
S
V
S
E
R
L
Q
S
D
L
Rat
Rattus norvegicus
NP_001163818
2343
257924
S1261
E
K
L
S
N
S
V
S
E
R
L
Q
S
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423893
2312
255194
V1228
S
D
L
I
V
C
I
V
I
G
V
L
Y
F
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923995
2285
252748
V1232
V
L
Y
F
A
I
H
V
S
T
V
F
I
A
L
Tiger Blowfish
Takifugu rubipres
Q98UF7
1703
191329
S673
S
V
N
E
R
L
Q
S
D
L
I
V
C
V
V
Fruit Fly
Dros. melanogaster
P18490
3433
367590
T1823
R
K
L
Q
A
T
V
T
T
R
L
K
N
D
L
Honey Bee
Apis mellifera
XP_624687
2092
236172
F1061
K
S
S
Q
H
I
L
F
S
I
F
A
G
L
L
Nematode Worm
Caenorhab. elegans
NP_492790
1634
183268
L604
P
L
I
C
L
R
L
L
R
G
G
F
S
Q
P
Sea Urchin
Strong. purpuratus
XP_001195494
2799
311472
S1312
D
K
L
K
K
S
V
S
E
R
L
Q
S
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.6
98.7
94.4
N.A.
90.9
91.1
N.A.
N.A.
84.9
N.A.
66.7
54.4
29.4
38.7
27.7
35.5
Protein Similarity:
100
98.1
99.4
96.4
N.A.
95.5
95.3
N.A.
N.A.
90.8
N.A.
77.7
63
42.9
55.5
41.8
49.2
P-Site Identity:
100
13.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
6.6
N.A.
6.6
6.6
46.6
6.6
6.6
80
P-Site Similarity:
100
53.3
100
100
N.A.
93.3
93.3
N.A.
N.A.
20
N.A.
13.3
26.6
80
33.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
0
0
0
0
0
8
0
8
8
% A
% Cys:
0
0
0
8
0
8
0
0
0
8
0
0
8
0
0
% C
% Asp:
8
8
0
0
0
8
0
0
8
0
0
0
0
54
0
% D
% Glu:
47
0
0
8
0
0
0
0
47
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
8
16
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
8
0
8
8
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
16
8
0
8
8
16
0
16
0
0
% I
% Lys:
8
54
0
8
8
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
16
70
0
8
8
24
8
0
8
54
8
0
8
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
39
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
0
0
0
24
0
0
8
0
0
0
0
47
0
8
0
% Q
% Arg:
8
8
0
24
8
8
0
0
8
54
0
0
0
0
0
% R
% Ser:
16
8
8
16
8
47
0
54
16
0
0
0
54
0
0
% S
% Thr:
0
0
0
0
0
8
0
8
8
8
0
0
0
0
0
% T
% Val:
8
8
0
0
8
0
54
24
8
0
16
16
0
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _